Kyle J. MacBeth, Ph.D. Williamsville East High School, Class of 1988  (Inducted 2017)

Kyle J. MacBeth, Ph.D., is currently Senior Director of Translational Development and Diagnostics at Celgene Corporation, an integrated global biopharmaceutical company based in San Francisco, CA.  At Celgene, Dr. MacBeth leads translational development for the myeloid franchise. His team delivers both clinical and non-clinical research supporting the development of drugs for patients with diseases including acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), myelofibrosis and beta-thalassemia. He has contributed to the development of products such as Vidaza and Revlimid, which are improving the quality of life and extending survival in thousands of patients with MDS and AML today.

Dr. MacBeth graduated ninth in his class from Williamsville East High School and competed on the state record-setting varsity men’s gymnastics team from 1984-1988. Following high school, he attended the University of Pittsburgh, competing on Pitt’s NCAA Division-1 Men’s Gymnastics Team for four years and graduating summa cum laude in 1992 with a bachelor’s degree in microbiology. In his senior year of college, he was awarded the University’s Blue and Gold Award, honoring the most outstanding combination of a student athlete and scholar.

He continued his academic career at Harvard University as a graduate student in the biological and biomedical sciences program. He was named an Albert J. Ryan Fellow in 1995, honoring scientific excellence and promise of future success in biomedical research, and received his Ph.D. in microbiology and molecular genetics from Harvard in 1996.

His professional career began at Millennium Pharmaceuticals in Cambridge, MA as a research scientist in the oncology franchise identifying and validating new cancer targets. In 2007, he moved to San Francisco to establish a translational research site for Celgene Corporation. Dr. MacBeth has expertise in myeloid cancer biology, epigenetics, and protein homeostasis. For the past 21 years, he has dedicated himself to the research and development of therapies for cancer patients. He has authored over 20 research articles in prominent journals including Nature, Nature Medicine and Journal of Clinical Oncology, and is an inventor on numerous patents. Dr. MacBeth is an active member of the American Association for Cancer Research, American Society of Hematology, and European Hematology Association.